| Mesalazine-associated benign intracranial hypertension in a patient with ulcerative colitis. | |
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MedLine Citation:
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PMID: 12834704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To report a case of benign intracranial hypertension related to mesalazine use. DESIGN: Observational case report. METHODS: A 23-year-old-woman with sudden visual loss, headache, and a history of ulcerative colitis treated with mesalazine underwent ophthalmologic examination, echography, magnetic resonance imaging, and lumbar puncture. RESULTS: The examinations disclosed benign intracranial hypertension that resolved when mesalazine was discontinued and recurred when the drug was restarted. CONCLUSIONS: We recommend periodic ocular fundus examination for patients undergoing long-term therapy with mesalazine, especially if decreased vision, headaches, or neck stiffness are present, to avoid potentially severe complications of intracranial hypertension |
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Authors:
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Nicola Rosa; Arcangelo Giamundo; Attilio Jura; Gennarfrancesco Iaccarino; Antonio Romano |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of ophthalmology Volume: 136 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2003 Jul |
Date Detail:
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Created Date: 2003-07-01 Completed Date: 2003-07-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 212-3 Citation Subset: AIM; IM |
Affiliation:
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Eye Department, 2nd University of Naples, Naples, Italy. nocola.rosa@unina2.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Inflammatory Agents, Non-Steroidal / adverse effects* Colitis, Ulcerative / drug therapy* Female Headache / chemically induced Humans Mesalamine / adverse effects* Optic Nerve / ultrasonography Pseudotumor Cerebri / chemically induced*, ultrasonography Vision Disorders / chemically induced |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 89-57-6/Mesalamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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