Document Detail


Merkel cell carcinoma after chronic lymphocytic leukemia: case report and literature review.
MedLine Citation:
PMID:  14663367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Increasing evidence supports an association of Merkel cell carcinoma (MCC) with immunodeficiency and neoplasia, and the management and outcome of these patients requires study. This report describes a 72-year-old man with newly diagnosed chronic lymphocytic leukemia (CLL) who developed MCC of his right upper extremity and died of bone marrow metastases at 8 months. In the five previously reported cases of MCC after CLL, a shorter time interval between the diagnosis of CLL and the onset of MCC was associated with a better prognosis. In contrast, in this case the near simultaneous onset of CLL and MCC was followed by a rapid, lethal outcome.
Authors:
Roxana Vlad; Timothy J Woodlock
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of clinical oncology     Volume:  26     ISSN:  1537-453X     ISO Abbreviation:  Am. J. Clin. Oncol.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-09     Completed Date:  2004-01-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8207754     Medline TA:  Am J Clin Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  531-4     Citation Subset:  IM    
Affiliation:
Department of Medicine, Unity Health System, Rochester, New York 14611, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Bone Marrow Neoplasms / secondary
Carcinoma, Merkel Cell / etiology*,  pathology,  secondary
Fatal Outcome
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / complications*
Male
Skin Neoplasms / etiology*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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