Document Detail

Menstrual migraine: intermittent prophylaxis with a timed-release pharmacological formulation of dihydroergotamine.
MedLine Citation:
PMID:  6616598     Owner:  NLM     Status:  MEDLINE    
An open study was performed on 20 women between 20 and 40 years of age in order to assess the effectiveness of a slow-release pharmacological formulation of dihydroergotamine in the prevention of menstrual migraine. Therapy was started two days prior to the expected date of menstruation and continued for five days after the onset of menstrual flow. Trial lasted for five months, four patients suspended the treatment: one because of side effects and three because of "ineffectiveness of drug". In the 16 patients who completed the study, there was a significant reduction both in intensity and duration of migraine compared to the month prior to treatment.
R D'Alessandro; G Gamberini; A Lozito; T Sacquegna
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cephalalgia : an international journal of headache     Volume:  3 Suppl 1     ISSN:  0333-1024     ISO Abbreviation:  Cephalalgia     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2008-02-11    
Medline Journal Info:
Nlm Unique ID:  8200710     Medline TA:  Cephalalgia     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  156-8     Citation Subset:  IM    
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MeSH Terms
Delayed-Action Preparations
Dihydroergotamine / therapeutic use*
Migraine Disorders / drug therapy*,  etiology,  prevention & control
Time Factors
Reg. No./Substance:
0/Delayed-Action Preparations; 511-12-6/Dihydroergotamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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