Document Detail

Menotropins as a possible risk factor for premature deliveries in triplet pregnancies.
MedLine Citation:
PMID:  1776505     Owner:  NLM     Status:  MEDLINE    
This study was undertaken in order to evaluate pregnancy outcome in three groups of triplet conceptions. Of 36 delivered triplet gestations, seven were spontaneous, 12 achieved using clomiphene citrate and 17 induced by menotropins. The mean gestational age (weeks) at delivery was 36.5 +/- 1.0 SD, for spontaneous and clomiphene citrate pregnancies it was 35.9 +/- 1.9 SD which differed significantly from that in pregnancies induced by menotropins which was 32.9 +/- 3.7 SD. Similarly, triplets born following menotropin treatment had a significantly lower gestational weight (g) of 1656 +/- 516 SD vs. 2015 +/- 198 SD and 2176 +/- 315 SD for spontaneous and clomiphene citrate gestations, respectively. It is concluded that triplets following menotropins are at an increased risk for premature delivery and low birth weight.
N Mordel; N Laufer; G Zajicek; D Dorembus; A Benshushan; J G Schenker; E Sadovsky
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  5     ISSN:  0951-3590     ISO Abbreviation:  Gynecol. Endocrinol.     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1992-03-03     Completed Date:  1992-03-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  197-201     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Hadassah Medical Center, Jerusalem, Israel.
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MeSH Terms
Clomiphene / adverse effects
Gestational Age
Infant, Low Birth Weight
Infant, Newborn
Menotropins / adverse effects*
Obstetric Labor, Premature / chemically induced*
Retrospective Studies
Risk Factors
Reg. No./Substance:
61489-71-2/Menotropins; 911-45-5/Clomiphene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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