| Meningovascular syphilis with a gumma of the midbrain. | |
MedLine Citation:
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PMID: 1836794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a patient with meningovascular syphilis who had a dorsal midbrain syndrome, cognitive dysfunction, and a left peripheral seventh nerve palsy. Magnetic resonance imaging (MRI) disclosed a large lesion of the midbrain and thalamus with intense enhancement of the interpeduncular cistern, both of which resolved after treatment with intravenous penicillin. The clinical features, radiographic appearance, and response to therapy suggest that this lesion was a focal syphilitic inflammatory process, or gumma. We conclude that MRI with intravenous contrast may reveal the full spectrum of pathologic involvement in neurosyphilis and, in certain situations, may obviate the need for biopsy of an associated mass lesion. |
Authors:
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D G Standaert; S L Galetta; S W Atlas |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of clinical neuro-ophthalmology Volume: 11 ISSN: 0272-846X ISO Abbreviation: J Clin Neuroophthalmol Publication Date: 1991 Sep |
Date Detail:
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Created Date: 1992-02-06 Completed Date: 1992-02-06 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8109051 Medline TA: J Clin Neuroophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 139-43 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Encephalitis / complications, pathology* Facial Paralysis / etiology Follow-Up Studies Humans Magnetic Resonance Imaging Male Mesencephalon* / pathology Neurosyphilis / complications, pathology* Penicillins / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Penicillins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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