Document Detail


Meningomyelocele: management in utero and post natum.
MedLine Citation:
PMID:  8005029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a four year follow-up of 39 of 47 infants born after pre-labour Caesarean section and 68 of 79 born vaginally. Loss of motor function due to late complications was more frequent in the Caesarean section group (Fisher's Exact; P = 0.004). However, the means of the differences between the X-ray levels (measured as the last intact vertebral arch seen on standard anteroposterior roentgenograms of the spinal column) subtracted from the motor levels still favour Caesarean section (mean = 3.24; SD = 2.7) over vaginal delivery (mean = 1.2; SD = 2.7) (Student's t-test; P = 0.0003). The frequencies of other complications, death and neonatal meningitis, were not significantly different. Another 38 infants born by Caesarean section after labour were more paralysed (mean of X-ray and motor difference = 1.8, SD = 2.2) following rupture of amniotic membranes than those with intact amniotic membranes with or without labour (mean = 3.4; SD = 2.2) (Student's t-test; P = 0.0067). The differences between X-ray and motor levels for patients born by Caesarean section with intact amniotic membranes and without labour (mean = 3.6; SD = 2.4) were not significantly different from those with labour and intact amniotic membranes (mean = 2.89; SD = 1.5). The number of new cases of meningomyelocele presenting to our clinic has decreased from an average of 30 per year between 1970 and 1987 to 14 between 1988 and 1992.
Authors:
D B Shurtleff; D A Luthy; D A Nyberg; T J Benedetti; L A Mack
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Ciba Foundation symposium     Volume:  181     ISSN:  0300-5208     ISO Abbreviation:  Ciba Found. Symp.     Publication Date:  1994  
Date Detail:
Created Date:  1994-07-21     Completed Date:  1994-07-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0356636     Medline TA:  Ciba Found Symp     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  270-80; discussion 280-6     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Washington, Seattle 98105.
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MeSH Terms
Descriptor/Qualifier:
Cesarean Section
Delivery, Obstetric / methods
Extraembryonic Membranes
Female
Follow-Up Studies
Humans
Meningomyelocele / complications,  diagnosis,  therapy*
Paralysis / etiology
Pregnancy
Prenatal Care*
Prenatal Diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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