Document Detail

Meningomyelocele: management in utero and post natum.
MedLine Citation:
PMID:  8005029     Owner:  NLM     Status:  MEDLINE    
We report a four year follow-up of 39 of 47 infants born after pre-labour Caesarean section and 68 of 79 born vaginally. Loss of motor function due to late complications was more frequent in the Caesarean section group (Fisher's Exact; P = 0.004). However, the means of the differences between the X-ray levels (measured as the last intact vertebral arch seen on standard anteroposterior roentgenograms of the spinal column) subtracted from the motor levels still favour Caesarean section (mean = 3.24; SD = 2.7) over vaginal delivery (mean = 1.2; SD = 2.7) (Student's t-test; P = 0.0003). The frequencies of other complications, death and neonatal meningitis, were not significantly different. Another 38 infants born by Caesarean section after labour were more paralysed (mean of X-ray and motor difference = 1.8, SD = 2.2) following rupture of amniotic membranes than those with intact amniotic membranes with or without labour (mean = 3.4; SD = 2.2) (Student's t-test; P = 0.0067). The differences between X-ray and motor levels for patients born by Caesarean section with intact amniotic membranes and without labour (mean = 3.6; SD = 2.4) were not significantly different from those with labour and intact amniotic membranes (mean = 2.89; SD = 1.5). The number of new cases of meningomyelocele presenting to our clinic has decreased from an average of 30 per year between 1970 and 1987 to 14 between 1988 and 1992.
D B Shurtleff; D A Luthy; D A Nyberg; T J Benedetti; L A Mack
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Ciba Foundation symposium     Volume:  181     ISSN:  0300-5208     ISO Abbreviation:  Ciba Found. Symp.     Publication Date:  1994  
Date Detail:
Created Date:  1994-07-21     Completed Date:  1994-07-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0356636     Medline TA:  Ciba Found Symp     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  270-80; discussion 280-6     Citation Subset:  IM    
Department of Pediatrics, University of Washington, Seattle 98105.
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MeSH Terms
Cesarean Section
Delivery, Obstetric / methods
Extraembryonic Membranes
Follow-Up Studies
Meningomyelocele / complications,  diagnosis,  therapy*
Paralysis / etiology
Prenatal Care*
Prenatal Diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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