Document Detail


Meningococcal pneumonia: characterization and review of cases seen over the past 25 years.
MedLine Citation:
PMID:  10619738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fifty-eight cases of meningococcal pneumonia were included in this review. Fifty cases previously described in the literature from 1974 through 1998 and 8 new cases were included in this series. The median age of patients was 57.5 years, and pleuritic chest pain was described in 21 (53.9%) of 39 cases. Blood cultures were positive in 42 (79.3%) of 53 cases for which results were mentioned. Despite the presence of bacteremia, patients did not develop the syndrome of meningococcemia with its associated complications. Serogroup Y meningococci were most commonly recovered and accounted for 44.2% of identified isolates. Therapy has dramatically changed over the past 25 years; prior to 1991, penicillin antibiotics were most often used. Since 1991, 12 (80%) of 15 patients received cephalosporin antibiotics. Only 5 (8.62%) of 58 patients died. Secondary cases of meningococcal infections following exposure to patients with meningococcal pneumonia were noted in 2 instances.
Authors:
J M Winstead; D S McKinsey; S Tasker; M A De Groote; L M Baddour
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  30     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-03-09     Completed Date:  2000-03-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  87-94     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of Tennessee Medical Center at Knoxville, Knoxville, TN 37920-6999, USA.
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MeSH Terms
Descriptor/Qualifier:
Age Distribution
Anti-Bacterial Agents / therapeutic use
Female
Humans
Male
Meningococcal Infections* / diagnosis,  drug therapy,  microbiology,  pathology
Neisseria meningitidis* / classification,  isolation & purification
Pneumonia, Bacterial* / diagnosis,  drug therapy,  microbiology,  pathology
Serotyping
Sex Distribution
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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