Document Detail

Meningococcal osteomyelitis in a premature infant.
MedLine Citation:
PMID:  15678709     Owner:  NLM     Status:  MEDLINE    
The authors report a rare case of acute hematogenous osteomyelitis in a premature very low-birth weight infant caused by Neisseria meningitidis, a microorganism which occasionally causes arthritis, but is very rarely involved in bone infections. The strong teamwork of clinicians, the clinical microbiologist and the radiologist allowed the prompt formulation and confirmation of the clinical suspect (regardless of the paucity of symptoms and systemic signs), the rapid isolation of the microorganism and the prompt initiation of a specific therapy, thus obviating the need for a more invasive bone biopsy, which would have been hazardous considering the risks associated with an invasive procedure, and much higher in our case because of the young age of the patient and his prematurity. Moreover, this case confirms that early ultrasonographic examination may anticipate the diagnosis and the initiation of therapy in case of a clinical suspicion of acute hematogenous osteomyelitis, thus avoiding serious complications such as growth disorders or arrest, shortening or angular deformity, loss of motion and degenerative osteoarthritis. In accordance with what suggested in the literature, initial parenteral treatment followed early by oral antibiotics was chosen, with an excellent outcome.
Alessandro Cigni; Sebastiana Cossellu; Andrea Porcu; Sergio Piga
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annali italiani di medicina interna : organo ufficiale della Società italiana di medicina interna     Volume:  19     ISSN:  0393-9340     ISO Abbreviation:  Ann. Ital. Med. Int.     Publication Date:    2004 Oct-Dec
Date Detail:
Created Date:  2005-01-31     Completed Date:  2005-03-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806705     Medline TA:  Ann Ital Med Int     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  280-2     Citation Subset:  IM    
Istituto di Patologia Medica, Università degli Studi di Sassari.
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MeSH Terms
Infant, Newborn
Infant, Premature, Diseases / diagnosis*,  microbiology,  ultrasonography
Infant, Very Low Birth Weight
Meningococcal Infections / diagnosis*,  microbiology,  ultrasonography
Neisseria meningitidis* / isolation & purification
Osteomyelitis / diagnosis*,  microbiology,  ultrasonography

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