| Meningococcal disease in Dallas County, Texas: results of a six-year population-based study. | |
| | |
MedLine Citation:
|
PMID: 10783023 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Neisseria meningitidis is an important cause of serious bacterial infection in children and adults in the US. From 1992 to 1997 invasive disease caused by N. meningitidis was studied among 1.9 million residents of Dallas County, TX METHODS: The demographic characteristics and diagnoses of 151 patients were identified through active, population-based surveillance and review of medical records. Serogroups were determined for strains infecting 129 (85%) patients. RESULTS: The average annualized incidence rate was 1.3 cases per 100,000 person years and was highest for children <1 year (13 cases/100,000 person years). Older patients (50+ years old) were more likely to present with pneumonia and less likely to present with meningitis than younger patients. Neither the fatality rate nor the duration of hospitalization for surviving patients was associated with age. Among patients with a known serogroup, serogroup C disease was found in 35% of cases <1 year old, 64% of those 1 to 49 years old and 44% of those 50+ years old. Serogroup B strains were isolated from 26% of patients <1 year, 17% of patients 1 to 49 years old and none of the patients 50+ years old. Serogroup Y disease increased from 22% to 35% of cases between 1992 and 1997 (P = 0.03). This serogroup was identified in 26% of patients <1 year old, 17% of patients 1 to 49 years old and in 50% of patients 50+ years old. Serogroup C and Y accounted for 61% of cases in children <1 year old and for 79% of cases in all age groups. CONCLUSION: The results underscore the importance of conjugate vaccines for serogroups C and Y. |
| | |
Authors:
|
P Pastor; F B Medley; T V Murphy |
Related Documents
:
|
17965803 - Ecthyma gangrenosum in saudi arabia. 9556703 - Bacterial arthritis due to beta-hemolytic streptococci of serogroups a, b, c, f, and g.... 310343 - Thymosin-inducible lymphocytes in the peripheral blood of patients with malignant melan... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Pediatric infectious disease journal Volume: 19 ISSN: 0891-3668 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 2000 Apr |
Date Detail:
|
Created Date: 2000-06-16 Completed Date: 2000-06-16 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 324-8 Citation Subset: IM |
Affiliation:
|
University of Texas Southwestern Medical Center, Dallas, USA. php3@cdc.gov |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Age Distribution Aged Aged, 80 and over Child Child, Preschool Female Humans Incidence Infant Infant, Newborn Male Meningococcal Infections / diagnosis*, epidemiology* Middle Aged Neisseria meningitidis / isolation & purification* Population Surveillance Risk Factors Sex Distribution Survival Rate Texas / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of M...
Next Document: Etiology and treatment of pneumonia.