Document Detail


Memory loss following radiotherapy for nasal pharyngeal carcinoma--an unusual presentation of amnesia.
MedLine Citation:
PMID:  1777756     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this article we describe a patient who developed amnesia several years after receiving a second course of radiotherapy treatment for nasopharyngeal cancer (NPC). Detailed assessment of memory indicated a marked anterograde impairment for verbal material with less impaired non-verbal memory. A dense retrograde deficit was also present, reflected in both poor event memory and loss of general knowledge. Performance on other tests indicated a mild intellectual deficit but no other cognitive impairments. The findings indicate a striking memory disorder arising from late temporal lobe necrosis. These findings stress the importance of assessing neuropsychological sequelae when evaluating the long-term outcome of radiotherapy for NPC and other cancers of the head and neck.
Authors:
A J Parkin; N M Hunkin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of clinical psychology / the British Psychological Society     Volume:  30 ( Pt 4)     ISSN:  0144-6657     ISO Abbreviation:  Br J Clin Psychol     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1992-03-09     Completed Date:  1992-03-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8105533     Medline TA:  Br J Clin Psychol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  349-57     Citation Subset:  IM    
Affiliation:
Laboratory of Experimental Psychology, University of Sussex, Brighton, UK.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amnesia / etiology*
Brain / radiation effects*
Follow-Up Studies
Frontal Lobe / radiation effects
Humans
Lymphatic Metastasis
Male
Mental Recall / radiation effects*
Nasopharyngeal Neoplasms / radiotherapy*
Neuropsychological Tests
Radiation Injuries / etiology*
Temporal Lobe / radiation effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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