Document Detail


Membranous nephropathy: its relative benignity in women.
MedLine Citation:
PMID:  7329469     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
By means of renal biopsy and light, immunofluorescence, and electron microscopy, a diagnosis of membranous nephropathy (MN) was made in 100 patients. The nephrotic syndrome was present in 83 of these patients. 65 of the patients were men and 35 were women. The average period of follow-up was 99.8 months. As judged by the incidence of death and of improvement or complete healing, the women fared better than the men, whether given high-dose alternate-day prednisone therapy or not. The incidence of improvement or complete healing in the patients given prednisone was higher than the reported for patients who were not given corticosteroids. We have shown that occurrence of MN is more frequent in women than men and the course of MN is more benign in women than in men; alternate-day prednisone therapy appears to be beneficial in patients with MN.
Authors:
J Hopper; P A Trew; C G Biava
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Nephron     Volume:  29     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1981  
Date Detail:
Created Date:  1982-04-20     Completed Date:  1982-04-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  18-24     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Biopsy
Female
Glomerulonephritis / diagnosis*,  drug therapy
Humans
Kidney / pathology,  ultrastructure
Male
Middle Aged
Nephrotic Syndrome / diagnosis*,  drug therapy
Prednisone / therapeutic use
Sex Factors
Grant Support
ID/Acronym/Agency:
AM-06579/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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