Document Detail


Membranous nephropathy complicating adenolymphoma of the parotid (Warthin's tumour).
MedLine Citation:
PMID:  8856273     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Membranous nephropathy has been described in association with many malignancies including various lymphomas. However, it has not been previously described as a complication of benign solid adenolymphoma of the parotid, also called Warthin's tumour. We describe a patient who presented with an adenolymphoma of the parotid, and developed a severe nephrotic syndrome due to membranous nephropathy 6 months after the parotid swelling. The nephrotic syndrome resolved following parotidectomy and a short course of immunosuppression with prednisolone and cyclophosphamide. The possible pathophysiologic mechanisms are discussed.
Authors:
S P Kon; S L Fan; J T Kwan; S M Dodd; M J Raftery
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Nephron     Volume:  73     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1996  
Date Detail:
Created Date:  1997-01-03     Completed Date:  1997-01-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  692-4     Citation Subset:  IM    
Affiliation:
Department of Renal Medicine and Transplantation and Histopathology, London Hospital Medical College, UK.
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MeSH Terms
Descriptor/Qualifier:
Adenolymphoma / complications*,  pathology,  surgery
Antineoplastic Agents, Alkylating / adverse effects,  therapeutic use
Antineoplastic Agents, Hormonal / adverse effects,  therapeutic use
Cyclophosphamide / adverse effects,  therapeutic use
Glomerulonephritis, Membranous / blood,  complications*,  pathology
Humans
Male
Middle Aged
Parotid Neoplasms / complications*,  pathology,  surgery
Prednisolone / adverse effects,  therapeutic use
Chemical
Reg. No./Substance:
0/Antineoplastic Agents, Alkylating; 0/Antineoplastic Agents, Hormonal; 50-18-0/Cyclophosphamide; 50-24-8/Prednisolone

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