| Membranoproliferative glomerulonephritis in a girl and her mother. | |
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MedLine Citation:
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PMID: 18641916 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A girl and her mother were diagnosed as having membranoproliferative glomerulonephritis (MPGN) type I. Microscopic hematuria and proteinuria presented at 9 years of age in the mother and at 14 years in the daughter. Both had persistent hypocomplementemia and were treated with steroids. When the mother was 40 years old, proteinuria was still continuing and creatinine clearance was 64.4 ml/min per 1.73 m(2). When the daughter was 15 years old, microscopic hematuria was still continuing. To our knowledge, familial cases of MPGN in two generations have not been reported in Japan. |
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Authors:
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Osamu Motoyama; Ken Sakai; Yasushi Ohashi; Sonoo Mizuiri; Tsutomu Hatori; Kikuo Iitaka; Yasushi Koitabashi |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-07-19 |
Journal Detail:
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Title: Clinical and experimental nephrology Volume: 13 ISSN: 1342-1751 ISO Abbreviation: Clin. Exp. Nephrol. Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-02 Completed Date: 2009-03-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9709923 Medline TA: Clin Exp Nephrol Country: Japan |
Other Details:
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Languages: eng Pagination: 77-80 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Toho University Medical Center, Sakura Hospital, 564-1 Shimoshizu, Sakura, Chiba, Japan. motoyan@basil.ocn.ne.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Biopsy Child Complement System Proteins / immunology Creatinine / blood Female Genetic Predisposition to Disease Glomerulonephritis, Membranoproliferative / complications, diagnosis*, drug therapy, genetics, immunology Hematuria / etiology Humans Kidney Glomerulus / immunology, metabolism, pathology* Pedigree Pregnancy Proteinuria / etiology Steroids / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Steroids; 60-27-5/Creatinine; 9007-36-7/Complement System Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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