| Membrane thickness design of implantable bio-MEMS sensors for the in-situ monitoring of blood flow. | |
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MedLine Citation:
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PMID: 17200811 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper presents some ideas for the membrane thickness design of of implantable bio-micro-electro-mechanical systems (bio-MEMS) for the in situ monitoring of blood flow. The objective is to develop a smart wireless sensing unit for non-invasive early stenosis detection in heart bypass grafts. The design includes considerations of nonlinear material models, multiscale blood flows, and appropriate analyical models for data interpretation, as well as preliminary studies of the pressure and flow sensing concepts. The paper also examines the use of surface coatings for the design on biocompatibility and non-adhesion of blood platelets and constituents. The implications of the results are discussed for in vivo deployment of such sensor systems. |
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Authors:
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C A Steeves; Y L Young; Z Liu; A Bapat; K Bhalerao; A B O Soboyejo; W O Soboyejo |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Journal of materials science. Materials in medicine Volume: 18 ISSN: 0957-4530 ISO Abbreviation: J Mater Sci Mater Med Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-01-03 Completed Date: 2007-05-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9013087 Medline TA: J Mater Sci Mater Med Country: United States |
Other Details:
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Languages: eng Pagination: 25-37 Citation Subset: IM |
Affiliation:
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Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biomedical Engineering / instrumentation, methods Biosensing Techniques / instrumentation*, methods Blood Flow Velocity / physiology* Blood Platelets / physiology Blood Vessel Prosthesis* Cardiopulmonary Bypass Cell Adhesion Coated Materials, Biocompatible / chemistry Constriction, Pathologic / etiology, physiopathology, prevention & control* Equipment Design Humans Materials Testing Miniaturization Models, Biological Monitoring, Physiologic* Reproducibility of Results Sensitivity and Specificity Surface Properties Transducers, Pressure |
| Chemical | |
Reg. No./Substance:
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0/Coated Materials, Biocompatible |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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