Document Detail

Membrane fusion and fission: enveloped viruses.
MedLine Citation:
PMID:  19601904     Owner:  NLM     Status:  MEDLINE    
Membrane fusion and fission are two key processes that occur during the replication of enveloped viruses, namely access to the interior of the host-cell (entry, which requires fusion of the viral envelope with the target cell envelope) and dissemination of viral progeny after replication (egress, which involves budding and fission). These dynamic processes are mediated by specialized proteins that modify and bend the lipid bilayer transiently and locally. This review focuses on fusion and fission reactions and on the hypothetical shared mechanism that generates their driving force.
Annarita Falanga; Marco Cantisani; Carlo Pedone; Stefania Galdiero
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Protein and peptide letters     Volume:  16     ISSN:  1875-5305     ISO Abbreviation:  Protein Pept. Lett.     Publication Date:  2009  
Date Detail:
Created Date:  2009-07-15     Completed Date:  2009-09-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9441434     Medline TA:  Protein Pept Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  751-9     Citation Subset:  IM    
Department of Biological Sciences, Division of Biostructures and Centro Interuniversitario di Ricerca sui Peptidi Bioattivi - University of Naples Federico II, and Istituto di Biostrutture e Bioimmagini - CNR, Via Mezzocannone 16, Napoli 80134, Italy.
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MeSH Terms
Cell Membrane / drug effects,  metabolism
Membrane Fusion*
Peptides / metabolism,  pharmacology
Viral Envelope Proteins / metabolism
Virus Internalization*
Viruses / metabolism*
Reg. No./Substance:
0/Peptides; 0/Viral Envelope Proteins

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