| Membrane dynamics of Friend leukaemic cells. II. Changes associated with cell differentiation. | |
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MedLine Citation:
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PMID: 7397778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a previous study, using fluorescence polarization (P) with diphenyl hexatriene (DPH), it was shown that growing and resting cells have different P-values. This property has now been used to investigate the membrane action of dimethylsulfoxide (DMSO) and hexamethylene bisacetamide (HMBA), two inducers of Friend leukaemic cell (FLC) differentiation. Both an inducible cell line (FLC) and a resistant variant cell line (RFLC), had the same characteristics regarding P-values. During the differentiation process in the FLC cell line, further changes in P-values were observed. In the resistant cell line, these changes in P-value were not seen. This suggests that these inducers of differentiation are acting at the cell membrane. |
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Authors:
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H Tapiero; A Fourcade; C Billard |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cell differentiation Volume: 9 ISSN: 0045-6039 ISO Abbreviation: Cell Differ. Publication Date: 1980 |
Date Detail:
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Created Date: 1980-10-24 Completed Date: 1980-10-24 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0342640 Medline TA: Cell Differ Country: IRELAND |
Other Details:
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Languages: eng Pagination: 211-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetamides
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pharmacology* Animals Cell Differentiation* / drug effects Cell Membrane / drug effects, metabolism* Cells, Cultured Diamines / pharmacology* Dimethyl Sulfoxide / pharmacology Diphenylhexatriene Drug Resistance Friend murine leukemia virus Leukemia, Experimental / metabolism* Mice Microscopy, Fluorescence Microscopy, Polarization |
| Chemical | |
Reg. No./Substance:
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0/Acetamides; 0/Diamines; 1720-32-7/Diphenylhexatriene; 3073-59-4/hexamethylene bisacetamide; 67-68-5/Dimethyl Sulfoxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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