Document Detail


Membrane-covered stents for the treatment of aortocoronary vein graft disease.
MedLine Citation:
PMID:  10816288     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report of a 78-year-old patient who underwent angioplasty for two de novo lesions in different aortocoronary venous bypass grafts. Whereas one lesion was treated by conventional stents, two adjacent lesions in a second bypass graft were covered by two newly designed stents with a polytetrafluorethylene (PTFE) membrane in between two layers of struts. The patient was first readmitted at month 5 with recurrent angina pectoris. High-grade in-stent restenosis of the lesion covered by the conventional stent was diagnosed, whereas the lesions treated by the membrane-covered stent revealed no restenosis. The patient underwent subsequent balloon angioplasty and was readmitted with unstable angina 8 months after the initial procedure. The angiogram revealed subtotal occlusion of the vein graft due to diffuse in-stent restenosis within the conventional stent. Undergoing re-PTCA, the patient received an additional membrane-covered stent placed over the proximal device. For the following 7 months, the patient stayed asymptomatic and underwent elective reangiography, which revealed a satisfying long-term result with no relevant luminal loss at the target site. This intraindividual comparison of stents in aortocoronary vein grafts suggests that PTFE membrane-covered stents might reduce restenosis as compared to conventional stents in venous bypass grafts. Furthermore, these stents potentially represent a new treatment strategy to fight in-stent restenosis in selected lesions.
Authors:
S Baldus; R Köster; J Reimers; C W Hamm
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  50     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-06-16     Completed Date:  2000-06-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  83-8     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Angina Pectoris / radiography,  therapy*
Angioplasty, Transluminal, Percutaneous Coronary / instrumentation*,  methods
Coated Materials, Biocompatible
Coronary Angiography
Coronary Artery Bypass / adverse effects*,  methods
Coronary Disease / surgery
Follow-Up Studies
Graft Occlusion, Vascular / radiography,  therapy*
Humans
Polytetrafluoroethylene*
Recurrence
Saphenous Vein / transplantation
Stents*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Coated Materials, Biocompatible; 9002-84-0/Polytetrafluoroethylene
Comments/Corrections
Comment In:
Catheter Cardiovasc Interv. 2000 May;50(1):89   [PMID:  10816289 ]

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