| Melatonin concentration in umbilical cord blood depends on mode of delivery. | |
| | |
MedLine Citation:
|
PMID: 22018695 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND AND AIMS: Melatonin (MT) is rapidly transferred from the maternal to fetal circulation in humans. There is little knowledge about factors which influence the MT concentration (MTc) in the umbilical cord (UC) blood during delivery. The aim of our study was to evaluate the MT status in the UC blood according to the time and mode of delivery. SUBJECTS AND METHODS: Blood samples from umbilical artery (UA) and vein (UV) were collected from spontaneous vaginal deliveries (SVD, n=122) and cesarean section deliveries (CSD, n=188). MTc was measured using a commercially available radioimmunoassay. RESULTS: The MTc was not significantly different between UA and UV blood both at daytime and at nighttime (p=0.216 and p=0.440, respectively). Both in UA and in UV, the MTc was significantly higher at nighttime than at daytime (p<0.0001). Compared with the CSD group, MTc in the SVD group was significantly higher both at night- and daytime (p<0.05). MTc both in UA and in UV was found to be not significantly different between patients with and without risk factors for stress including pregnancy complications (e.g., preeclampsia) and intrapartum complications (e.g., emergency section, pathological doppler, and pathological cardiotocography) (p>0.05). CONCLUSION: Our study revealed for the first time that MTc both in UA and in UV depends on modus of labor. In agreement with other studies, we found a clear circadian MT rhythm in the UC blood of neonates. The results of our study may suggest to a physiological role of MT at the onset of labor. |
| | |
Authors:
|
Soyhan Bagci; Anna Lena Berner; Jochen Reinsberg; Anne-Sybil Gast; Berndt Zur; Lars Welzing; Peter Bartmann; Andreas Mueller |
Related Documents
:
|
9987065 - The development of x-ray imaging to study renal function. 2859065 - The role of alpha-adrenoceptors in the regulation of renal tubular sodium reabsorption ... 9393935 - Prevention of hypoxemia-induced renal dysfunction by perindoprilat in the rabbit. 104935 - The effect of dopamine on renal cortical blood flow in baboons with experimentally indu... 11498685 - molecular epidemiological study on hiv-1 infection in shandong province 6830865 - Interaction of liposomes with human leukocytes in whole blood. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-10-20 |
Journal Detail:
|
Title: Early human development Volume: - ISSN: 1872-6232 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-10-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7708381 Medline TA: Early Hum Dev Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Department of Neonatology, Children's Hospital, University of Bonn, Bonn, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: MR measurement of critical phase transition dynamics and supercritical fluid dynamics in capillary a...
Next Document: The relation of maternal job strain and cortisol levels during early pregnancy with body composition...