| Melatonin and Mental Capacities in Newborn Infants. | |
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MedLine Citation:
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PMID: 21315375 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES: To investigate the role of melatonin in the emergence of mental capacities in the newborn infant. STUDY DESIGN: Assessment of Preterm Infant Behavior examination was performed at 2 weeks post-term age for 39 (21 preterm and 18 term) infants. 6-Suphatoxymelatonin from nocturnal urine samples was analyzed by enzyme-linked immunosorbent assays, and the Mental Developmental Index, assessed by Bayley scales, was correlated at 4, 6, and 9 months' corrected age. RESULTS: Multivariate analysis of variance with repeated measures showed that improved autonomic function at 2 weeks of age was associated with higher Mental Developmental Index scores at 9 months when related to the amount of melatonin at 4, 6, and 9 months of age. CONCLUSIONS: Early compromised autonomic system function in preterm infants is associated with lower mental capacities and is related to lower melatonin levels at later ages. |
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Authors:
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Sari Goldstein Ferber; Heidelise Als; Gloria McAnulty; Hava Peretz; Nava Zisapel |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-9 |
Journal Detail:
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Title: The Journal of pediatrics Volume: - ISSN: 1097-6833 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Mosby, Inc. All rights reserved. |
Affiliation:
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Department of Neurobiology, Tel Aviv University, Tel Aviv, Israel. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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