Document Detail

Meiotic spindle presence and oocyte morphology do not predict clinical ICSI outcomes: a study of 967 transferred embryos.
MedLine Citation:
PMID:  17169176     Owner:  NLM     Status:  MEDLINE    
With a view to correlating oocyte morphology and meiotic spindle presence to clinical intracytoplasmic sperm injection (ICSI) outcomes, 967 oocytes that led to 967 transferred embryos in 404 embryo transfers were studied. No relationship was found between oocyte morphology (ooplasm texture, perivitelline space largeness, perivitelline space granulation absence/presence and the first polar body shape) or meiotic spindle presence or absence and clinical pregnancy per transfer and implantation rates after ICSI. It was concluded that oocyte morphology and meiotic spindle presence or absence can only predict fertilization, cleavage rates and embryo quality, as previously described in the literature, but do not help in daily ICSI practice in the choice of the metaphase II oocyte that will lead to the embryo that starts clinical pregnancy.
S Chamayou; C Ragolia; C Alecci; G Storaci; E Maglia; E Russo; A Guglielmino
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  13     ISSN:  1472-6483     ISO Abbreviation:  Reprod. Biomed. Online     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-12-15     Completed Date:  2007-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  England    
Other Details:
Languages:  eng     Pagination:  661-7     Citation Subset:  IM    
Unità di Medicina della Riproduzione - FOUDATION HERA, Viale Marco Polo 39/A, 95126 Catania, Italy.
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MeSH Terms
Embryo Implantation / physiology*
Embryo Transfer*
Infertility / therapy
Metaphase / physiology*
Oocytes / cytology*
Predictive Value of Tests
Pregnancy Maintenance
Retrospective Studies
Sperm Injections, Intracytoplasmic*

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