Document Detail


Megacystis, megacolon, and malrotation: A new syndromic association?
MedLine Citation:
PMID:  21739599     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Chronic intestinal pseudo-obstruction (CIPO) can occur as a consequence of neuropathies including diffuse Intestinal Neuronal Dysplasia (IND), a relatively rare enteric nervous system (ENS) abnormality. Although various authors reported of diffuse IND associated either with intestinal malrotation or megacystis, the co-existence of these three entities in the same patient has never been described before. The aim of this paper is to report for the first time in literature a series of patient with such association, focusing on one who carries a de novo duplication of chromosome 12, suggesting a new syndromic association (megacolon, megacystis, malrotation). © 2011 Wiley-Liss, Inc.
Authors:
A Pini Prato; V Rossi; M Fiore; S Avanzini; G Mattioli; F Sanfilippo; A Michelazzi; S Borghini; N Disma; G Montobbio; A Barabino; P Nozza; I Ceccherini; S Gimelli; V Jasonni
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-7
Journal Detail:
Title:  American journal of medical genetics. Part A     Volume:  -     ISSN:  1552-4833     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235741     Medline TA:  Am J Med Genet A     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
Affiliation:
Department of Pediatric Surgery, Giannina Gaslini Institute, Genoa, Italy. apinipr@tin.it.
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