Document Detail

Mefloquine-induced pneumonitis.
MedLine Citation:
PMID:  16706949     Owner:  NLM     Status:  MEDLINE    
Mefloquine is indicated as oral treatment and as prophylaxis for malaria in areas where chloroquine-resistant malaria is present. Gastrointestinal and neuropsychiatric side effects of mefloquine are well known. More severe neuropsychiatric disorders such as psychosis, depression, hallucinations, and seizures are also reported in the literature. We are reporting a case of drug-induced pneumonia due to mefloquine. This diagnosis was confirmed 4 months after the adverse event, after restarting the same malaria prophylaxis, which could be considered as an unintentional provocation test. This is the third case report in the literature of acute lung injury caused by mefloquine.
Patrick Soentjens; Marc Delanote; Alfons Van Gompel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of travel medicine     Volume:  13     ISSN:  1195-1982     ISO Abbreviation:  J Travel Med     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-05-18     Completed Date:  2006-08-02     Revised Date:  2009-07-07    
Medline Journal Info:
Nlm Unique ID:  9434456     Medline TA:  J Travel Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  172-4     Citation Subset:  IM    
Department of Internal Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
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MeSH Terms
Antimalarials / administration & dosage,  adverse effects*
Malaria / prevention & control*
Mefloquine / administration & dosage,  adverse effects*
Middle Aged
Pneumonia / chemically induced*,  diagnosis
Reg. No./Substance:
0/Antimalarials; 53230-10-7/Mefloquine

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