| Meeting report on the second targeted tumor therapies. | |
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MedLine Citation:
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PMID: 20053770 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This meeting report on the fourth Fabisch Symposium for Cancer Research and Molecular Biology describes the aims of the international meeting, the main topics of the presentations, and the highlights of the conference. The fourth Fabisch Symposium was the second on Targeted Tumor Therapies and held from April 1-3, 2009 in Berlin, Germany. The meeting focused on noncarrier-based targeted tumor therapies and their clinical application. The world's leading experts in this field presented the state of the art on tumor-specific targeting and tumor growth inhibition, drug design and production, and the description of innovative strategies for improved delivery. The topics concentrated on immunotoxins and other targeted toxins as anticancer drugs, thus providing a specialized meeting platform not existing elsewhere for these therapeutics. Although a number of innovative approaches on the avoidance of immune responses against highly effective toxins were presented, a notable conclusion of the meeting and direction for future research is the acute need to further reduce the immunogenicity of the targeted toxins, which hampers the efficacy of this group of therapeutics in clinical studies. The meeting successfully fostered plans for further research and cooperation between different groups to hopefully achieve advanced translational and clinical studies. |
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Authors:
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Christopher Bachran; Hendrik Fuchs |
Publication Detail:
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Type: Congresses; Research Support, Non-U.S. Gov't Date: 2010-01-06 |
Journal Detail:
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Title: Molecular cancer therapeutics Volume: 9 ISSN: 1538-8514 ISO Abbreviation: Mol. Cancer Ther. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-01-13 Completed Date: 2010-03-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101132535 Medline TA: Mol Cancer Ther Country: United States |
Other Details:
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Languages: eng Pagination: 17-23 Citation Subset: IM |
Affiliation:
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Zentralinstitut f?r Laboratoriumsmedizin und Pathobiochemie, Charit?-Universit?tsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antibodies, Neoplasm / immunology Clinical Trials as Topic Drug Delivery Systems* Drug Screening Assays, Antitumor Drug Therapy, Combination Humans Immunotoxins / pharmacology Neoplasms / immunology, therapy* Prodrugs / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Neoplasm; 0/Immunotoxins; 0/Prodrugs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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