| Meeting report on the 3rd International Congress on Developmental Origins of Health and Disease (DOHaD). | |
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MedLine Citation:
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PMID: 17413866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Developmental origins of health and disease (DOHaD) focuses on the earliest stages of human development, and provides a novel paradigm to complement other strategies for lifelong prevention of common chronic health conditions. The 3 International Congress on DOHaD, held in 2005, retained the most popular features from the first two biannual Congresses, while adding a number of innovations, including increased emphasis on implications of DOHaD for the developing world; programs for trainees and young investigators; and new perspectives, including developmental plasticity, influences of social hierarchies, effects of prematurity, and populations in transition. Emerging areas of science included, first, the controversial role of infant weight gain in predicting adult obesity, diabetes, and cardiovascular disease. Second, in the era of epidemic obesity, paying attention to the over-nourished fetus is as important as investigating the growth retarded one. Third, environmental toxins appear to have abroad range of long-lasting effects on the developing human. Fourth, epigenetic mechanisms could unite several strands of human and animal observations, and explain how genetically identical individuals raised in similar postnatal environments can nonetheless develop widely differing phenotypes. Improving the environment to which an individual is exposed during development may be as important as any other public health effort to enhance population health world wide. |
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Authors:
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Matthew W Gillman; David Barker; Dennis Bier; Felino Cagampang; John Challis; Caroline Fall; Keith Godfrey; Peter Gluckman; Mark Hanson; Diana Kuh; Peter Nathanielsz; Penelope Nestel; Kent L Thornburg |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Pediatric research Volume: 61 ISSN: 0031-3998 ISO Abbreviation: Pediatr. Res. Publication Date: 2007 May |
Date Detail:
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Created Date: 2007-06-05 Completed Date: 2007-07-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0100714 Medline TA: Pediatr Res Country: United States |
Other Details:
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Languages: eng Pagination: 625-9 Citation Subset: IM |
Affiliation:
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Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA. matthew_gillman@hms.harvard.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Animals Child Child, Preschool Congresses as Topic* Environmental Pollutants Epigenesis, Genetic Female Fetal Development* Health* Humans Infant Infant, Newborn Male Obesity / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
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K24 HL 068041/HL/NHLBI NIH HHS; R13 HD 051239/HD/NICHD NIH HHS; //Wellcome Trust |
| Chemical | |
Reg. No./Substance:
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0/Environmental Pollutants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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