Document Detail


Meeting the (N-terminal) end with acetylation.
MedLine Citation:
PMID:  21854977     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Cell-fate decisions are tightly linked to cellular energy status. In this issue, Yi et al. (2011) introduce a mechanism by which Bcl-xL lowers the threshold for apoptosis by suppressing acetyl-CoA production, which, in turn, suppresses the N-alpha-acetylation important for activation of the proapoptotic protease caspase-2.
Authors:
Joshua L Andersen; Sally Kornbluth
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell     Volume:  146     ISSN:  1097-4172     ISO Abbreviation:  Cell     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  503-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.
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