Document Detail

Medulloblastoma and birth date: evaluation of 3 U.S. datasets.
MedLine Citation:
PMID:  16053206     Owner:  NLM     Status:  MEDLINE    
Studies from Norway and Japan have found a higher incidence of medulloblastoma related to births that occur in the fall. The authors sought further evidence concerning this association. For 122 patients in a Duke University database and 90 patients from the Central Cancer Registry of North Carolina, the frequency distribution of birth dates by month was statistically significantly different from the expected North Carolina distribution (p = 0.04 and 0.06). For 75 patients from California Surveillance, Epidemiology, and End Results (SEER) data, the frequency distribution of birth dates by month was marginally different from the expected U.S. distribution (p = 0.14). For 922 patients from national SEER data, the frequency distribution of birth dates by month was not statistically significantly different from the expected U.S. distribution (p = 0.54). Subgroup analysis suggests seasonality of birth dates is most significant for patients aged 5-14 yr diagnosed with medulloblastoma.
Edward C Halperin; Marie L Miranda; Dorothy M Watson; Stephen L George; Matthew Stanberry
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of environmental health     Volume:  59     ISSN:  0003-9896     ISO Abbreviation:  Arch. Environ. Health     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2005-08-01     Completed Date:  2005-08-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0212627     Medline TA:  Arch Environ Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  26-30     Citation Subset:  AIM; IM    
Department of Radiation Oncology and Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
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MeSH Terms
Brain Neoplasms / epidemiology*,  etiology
Child, Preschool
Databases as Topic
Environmental Exposure / adverse effects*,  analysis
Infant, Newborn
Medulloblastoma / epidemiology*,  etiology
North Carolina / epidemiology
SEER Program*
Time Factors
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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