| Medium optimization by response surface methodology for poly-gamma-glutamic acid production using dairy manure as the basis of a solid substrate. | |
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MedLine Citation:
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PMID: 15846485 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dairy manure, supplemented with agro-industrial materials, was used as the solid substrate for high yield of poly-gamma-glutamic acid (gamma-PGA) by Bacillus subtilis CCTCC202048. The solid-state fermentation medium was optimized by response surface methodology. In the first optimization step, a Plackett-Burman design was used to evaluate the influence of related factors. Wheat bran, soybean cake and glutamic acid were found to be more compatible supplement with dairy manure and positively influenced on gamma-PGA production. In the second step, the concentrations of the three supplemental nutrients above were further optimized using a Box-Behnken design. The average gamma-PGA yield (4.70%) in triplicate under optimal conditions was obtained on the laboratory scale, whereas it was 3.58% at compost experiment. These would lay a foundation for lessening the pollution of dairy manure, increasing fertilizer efficiency and exploring a late-model organic fertilizer that retains water and nutrients. |
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Authors:
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Chen Xiong; Chen Shouwen; Sun Ming; Yu Ziniu |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2005-04-22 |
Journal Detail:
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Title: Applied microbiology and biotechnology Volume: 69 ISSN: 0175-7598 ISO Abbreviation: Appl. Microbiol. Biotechnol. Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2005-12-26 Completed Date: 2006-02-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8406612 Medline TA: Appl Microbiol Biotechnol Country: Germany |
Other Details:
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Languages: eng Pagination: 390-6 Citation Subset: IM |
Affiliation:
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State Key Laboratory of Agricultural Microbiology, National Engineering Research Centre of Microbial Pesticides, Huazhong Agricultural University, Wuhan 430070, People's Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bacillus subtilis / metabolism* Bacteriological Techniques / methods Cattle Colony Count, Microbial Culture Media* Dairying* Fermentation Industrial Microbiology / methods Manure* Polyglutamic Acid / biosynthesis* Substrate Specificity |
| Chemical | |
Reg. No./Substance:
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0/Culture Media; 0/Manure; 25513-46-6/Polyglutamic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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