Document Detail


Medicinal chemistry and the pharmacy curriculum.
MedLine Citation:
PMID:  22102751     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The origins and advancements of pharmacy, medicinal chemistry, and drug discovery are interwoven in nature. Medicinal chemistry provides pharmacy students with a thorough understanding of drug mechanisms of action, structure-activity relationships (SAR), acid-base and physicochemical properties, and absorption, distribution, metabolism, excretion, and toxicity (ADMET) profiles. A comprehensive understanding of the chemical basis of drug action equips pharmacy students with the ability to answer rationally the "why" and "how" questions related to drug action and it sets the pharmacist apart as the chemical expert among health care professionals. By imparting an exclusive knowledge base, medicinal chemistry plays a vital role in providing critical thinking and evidence-based problem-solving skills to pharmacy students, enabling them to make optimal patient-specific therapeutic decisions. This review highlights the parallel nature of the history of pharmacy and medicinal chemistry, as well as the key elements of medicinal chemistry and drug discovery that make it an indispensable component of the pharmacy curriculum.
Authors:
M O Faruk Khan; Michael J Deimling; Ashok Philip
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of pharmaceutical education     Volume:  75     ISSN:  1553-6467     ISO Abbreviation:  Am J Pharm Educ     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-11-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372650     Medline TA:  Am J Pharm Educ     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161     Citation Subset:  IM    
Affiliation:
College of Pharmacy, Southwestern Oklahoma State University.
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