Document Detail


Medications used in the treatment of hypoglycemia due to congenital hyperinsulinism of infancy (HI).
MedLine Citation:
PMID:  16456495     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Congenital hyperinsulinism of infancy is the commonest cause of persistent and recurrent hypoglycaemia in the neonatal and infancy period. It is a heterogeneous disorder with respect to clinical presentation, histology, molecular biology and genetics. The biochemical profile is one of hypoketotic, hypofattyacidemic hypoglycemia. To prevent permanent brain damage from hypoglycemia, the treatment of infants with congenital hyperinsulinism must be prompt and aggressive. The drugs used in the medical therapy for congenital hyperinsulinism are diazoxide, octreotide, glucagon and nifedipine.
Authors:
Khalid Hussain; Albert Aynsley-Green; Charles A Stanley
Related Documents :
10569405 - Laryngomalacia and its treatment.
21481015 - Preterm and term neonates transplacentally acquire igg antibodies specific to lps from ...
8323365 - Isolated single umbilical artery--the case for routine renal screening.
6683075 - Interstitial deletion 2q31 leads to q33.
8298125 - Clonal, nonconstitutional rearrangements of the mll gene in infant twins with acute lym...
17188615 - Lethal fetal and early neonatal presentation of adenylosuccinate lyase deficiency: obse...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Pediatric endocrinology reviews : PER     Volume:  2 Suppl 1     ISSN:  1565-4753     ISO Abbreviation:  Pediatr Endocrinol Rev     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2006-02-03     Completed Date:  2006-02-27     Revised Date:  2008-04-09    
Medline Journal Info:
Nlm Unique ID:  101202124     Medline TA:  Pediatr Endocrinol Rev     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  163-7     Citation Subset:  IM    
Affiliation:
The London Centre for Paediatric Endocrinology and Metabolism, Great Ormond Street Hospital for Children NHS Trust WC1N 3JH and the Institute of Child Health, University College London, WC1N 1EH United Kingdom. K.Hussain@ich.ucl.ac.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Diazoxide / therapeutic use
Gastrointestinal Agents / therapeutic use*
Glucagon / therapeutic use
Humans
Hypoglycemia / congenital,  drug therapy*
Infant
Nifedipine / therapeutic use
Octreotide / therapeutic use*
Persistent Hyperinsulinemia Hypoglycemia of Infancy / drug therapy*
Vasodilator Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Gastrointestinal Agents; 0/Vasodilator Agents; 21829-25-4/Nifedipine; 364-98-7/Diazoxide; 83150-76-9/Octreotide; 9007-92-5/Glucagon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Insulins and oral hypoglycemic medications.
Next Document:  Lipid-lowering medications.