| Medication use patterns in HIV-positive patients. | |
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MedLine Citation:
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PMID: 10128360 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with HIV infection or AIDS often receive several medications for treatment or prevention of their primary disease and/or associated complications. The objective of this study was to document patterns of drug use in an HIV-positive, outpatient population. Data were collected via one-on-one interviews with 26 HIV-positive patients; prescription and non-prescription drug use, adverse drug reactions and drug allergies were recorded. Anti-retroviral therapy was received by over 90 % of the patients. Over 90% of patients were on anti-infective agents, commonly cotrimoxazole or dapsone, while 27% received acyclovir. At least 70% of patients used three or more prescription medications concurrently. Every patient reported self-medicating with at least one over-the-counter (OTC) product and over half used three or more OTC products concurrently. Adverse reactions, mainly attributable to zidovudine, were reported by over 80% of patients. Non-compliance was a common drug-related issue; over 70% of patients omitted drug doses. In conclusion, the use of multiple medications in the ambulatory HIV-positive patients presents the health care team with potential drug-related problems that may ultimately affect the efficacy and toxicity of therapy. Thus pharmacists may play an active role in the provision of direct care to these patients. |
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Authors:
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R Chow; T Chin; I W Fong; R Bendayan |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Canadian journal of hospital pharmacy Volume: 46 ISSN: 0008-4123 ISO Abbreviation: Can J Hosp Pharm Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1993-10-15 Completed Date: 1993-10-15 Revised Date: 2009-10-12 |
Medline Journal Info:
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Nlm Unique ID: 0215645 Medline TA: Can J Hosp Pharm Country: CANADA |
Other Details:
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Languages: eng Pagination: 171-5 Citation Subset: H; X |
Affiliation:
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Princess Margaret Hospital, Toronto. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Data Collection Drug Prescriptions Drug Therapy / utilization* Evaluation Studies as Topic HIV Infections / drug therapy* Humans Male Middle Aged Nonprescription Drugs Ontario Outpatient Clinics, Hospital Outpatients / statistics & numerical data Patient Compliance Pharmacy Service, Hospital / statistics & numerical data* |
| Chemical | |
Reg. No./Substance:
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0/Nonprescription Drugs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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