Document Detail


Medication use in the treatment of migraine during pregnancy and lactation.
MedLine Citation:
PMID:  19728967     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Migraine is very common in women of reproductive age. With peak prevalence of migraine occurring during childbearing years, many women with migraine may knowingly or unknowingly use medication during pregnancy. Although migraine tends to improve during pregnancy, many women may still experience moderate to severe disabling headache and need pharmacologic treatment for the pain, nausea, and vomiting. This article explores the physiologic changes occurring during pregnancy that can affect pharmacokinetic properties of drugs and their metabolism. Acute and preventive treatment of migraine during pregnancy and lactation is discussed, with an emphasis on safety to the fetus and nursing infant. Safety and recommended use of medication during pregnancy may be different when use is considered during breastfeeding. A goal of treatment is to balance potential risk of treatment to the fetus and nursing infant with significant relief and return to normal function of the mother.
Authors:
Sylvia Lucas
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current pain and headache reports     Volume:  13     ISSN:  1534-3081     ISO Abbreviation:  Curr Pain Headache Rep     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100970666     Medline TA:  Curr Pain Headache Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  392-8     Citation Subset:  IM    
Affiliation:
The Headache Center, University of Washington Medical Center, 1959 NE Pacific Street, Box 356097, Seattle, WA 98195, USA. lucass@u.washington.edu
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