Document Detail


Medication-induced adverse effects: important concepts for the hand therapist.
MedLine Citation:
PMID:  20189757     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
NARRATIVE REVIEW: Myopathy, fracture, tendon rupture, and neuropathy are severe physical adverse effects associated with commonly prescribed medications. Recognition of and exercise adjustment for these medication-induced effects by the therapist is essential to providing adequate care. The normal structure and function of muscle, tendon, cartilage, or bone may be altered by medications, leading to significant disability. The number of patients presenting to therapists with medication-induced physical complaints is rising with increases in medication utilization. Therapists should be involved in adverse effect risk reduction by 1) identification and reporting of potential adverse medication reactions, 2) adjustment of exercise regimen when the patient is on a medication with potential damaging effects on tendon, muscle, or cartilage, and 3) vigilant screening for medication-induced myopathies, fractures, neuropathies, and tendinopathies. Although many medications induce physical adverse effects, understanding the most serious musculoskeletal effects of commonly prescribed medications is critical for therapists. LEVEL OF EVIDENCE: 5.
Authors:
Daniel M Riche; John D Cleary; S Travis King
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Publication Detail:
Type:  Journal Article     Date:  2010-03-01
Journal Detail:
Title:  Journal of hand therapy : official journal of the American Society of Hand Therapists     Volume:  23     ISSN:  0894-1130     ISO Abbreviation:  J Hand Ther     Publication Date:    2010 Apr-Jun
Date Detail:
Created Date:  2010-04-30     Completed Date:  2010-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8806591     Medline TA:  J Hand Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  230-6; quiz 237     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Hanley & Belfus. Published by Elsevier Inc. All rights reserved.
Affiliation:
University of Mississippi School of Pharmacy, Jackson, Mississippi, USA. driche@sop.umsmed.edu
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MeSH Terms
Descriptor/Qualifier:
Fractures, Bone / etiology
Humans
Musculoskeletal Diseases / chemically induced*
Osteoporosis / chemically induced
Peripheral Nervous System Diseases / chemically induced*
Pharmaceutical Preparations / adverse effects*
Physical Therapy (Specialty)
Wound Healing
Chemical
Reg. No./Substance:
0/Pharmaceutical Preparations

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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