| Medication errors: an important component of nonadherence to medication in an outpatient population of lung transplant recipients. | |
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MedLine Citation:
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PMID: 17868069 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Data about medication errors in outpatients are limited. Medication errors, defined as discordance between the most recent flow-sheet version, the patient's diary card or the contents of the pill container were assessed systematically after announcement in an outpatient setting of lung transplant recipients by a direct observation approach. A total of 101 patients took a median of 15 (13-17) different drugs and 31 (26-38) pills daily. A total of 2253 doses of drugs were further analyzed. A total of 152 errors were identified resulting in 303 incorrect doses. Lack of keeping a diary card was the only factor significantly associated with a higher rate of incorrect doses (regression coefficient 0.24, p = 0.02). Furthermore, a significant correlation of medication errors with clinical adverse events could be demonstrated. This study shows that medication errors are frequent in a population which has to comply with a complex drug regimen. The need for error control as a basic requirement for drug adherence must be accentuated. Mostly, medication errors seem to occur system-based. Therefore, redundant error control mechanisms and alertness of both the patient and the care-giver should be initiated systematically. |
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Authors:
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S Irani; P Seba; R Speich; A Boehler |
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Publication Detail:
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Type: Journal Article Date: 2007-09-14 |
Journal Detail:
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Title: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Volume: 7 ISSN: 1600-6135 ISO Abbreviation: Am. J. Transplant. Publication Date: 2007 Nov |
Date Detail:
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Created Date: 2007-10-11 Completed Date: 2008-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100968638 Medline TA: Am J Transplant Country: Denmark |
Other Details:
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Languages: eng Pagination: 2561-6 Citation Subset: IM |
Affiliation:
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Clinic of Pulmonary Medicine, University Hospital Zurich, Zurich, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Drug Therapy, Combination Female Follow-Up Studies Humans Immunosuppressive Agents / therapeutic use Lung Transplantation / immunology, psychology* Male Medical Errors / statistics & numerical data* Middle Aged Outpatients* Patient Dropouts / statistics & numerical data* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Immunosuppressive Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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