| Medication adherence in combat veterans with traumatic brain injury. | |
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MedLine Citation:
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PMID: 21258030 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Purpose Medication adherence in combat veterans with traumatic brain injury (TBI) was evaluated. Methods Patients with a diagnosis of TBI were identified by a computer search of veterans enrolled in the Operation Enduring Freedom/Operation Iraqi Freedom or TBI/polytrauma clinics at Durham Veterans Affairs Medical Center (VAMC) between September 15, 2007, and September 15, 2008. Patients were included if they were at least 18 years old, received medical care and medications at the VAMC for at least 12 continuous months, and were taking at least one maintenance medication. A randomly selected age-matched comparator group without TBI was obtained through a computer-generated convenience sample. A composite adherence score for each patient was calculated using the medication possession ratio (MPR). The most commonly prescribed medications and indicators of increased adherence among the TBI group were also identified. Results The composite MPR did not significantly differ between groups. The most commonly prescribed medications were selective serotonin-reuptake inhibitors and serotonin-norepinephrine-reuptake inhibitors and other antidepressants; however, these classes were associated with the lowest adherence rates. Factors associated with increased adherence included taking more than five maintenance medications (78%), living with a spouse or significant other (77%), owning a memory-assistance device (74%), and comorbid diagnosis of posttraumatic stress disorder (PTSD) (74%). Conclusion Medication adherence rates were similar among combat veterans with a diagnosis of TBI and an age-matched comparator group. Factors associated with increased adherence included taking more than five maintenance medications, living with a spouse or significant other, owning a memory-assistance device, and a comorbid diagnosis of PTSD. |
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Authors:
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Jenna Minton Huggins; Jamie N Brown; Bruce Capehart; Mary L Townsend; Jenny Legge; S Dee Melnyk |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists Volume: 68 ISSN: 1535-2900 ISO Abbreviation: Am J Health Syst Pharm Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9503023 Medline TA: Am J Health Syst Pharm Country: United States |
Other Details:
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Languages: eng Pagination: 254-8 Citation Subset: IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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