| Medical treatment of hirsutism. | |
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MedLine Citation:
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PMID: 18844711 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hirsutism is usually the result of an underlying adrenal, ovarian, or central endocrine abnormality mainly due to polycystic ovary syndrome but may also be idiopathic or drug induced. The aim of medical treatment of hirsutism is to rectify any causal hormonal balance, slow down or stop excessive hair growth, and improve the aesthetic appearance of hirsutism, thereby positively affecting the patient's quality of life. Today, for the majority of women, a monotherapy with oral contraceptives that have antiandrogenic activity is recommended as a first-line treatment for hirsutism. Combining an oral contraceptive pill with an antiandrogen is recommended if clinical improvement of hirsutism is insufficient after 6-9 months' monotherapy. In women who present with hirsutism, hyperandrogenism, and insulin resistance, insulin sensitizers are effective for the hirsutism as well as the hyperinsulinemia, hyperandrogenism, and infertility but there is no convincing evidence that they are effective for hirsutism alone. Topical eflornithine is a medical therapy that can be a useful adjuvant for hirsutism when used in conjunction with systemic medications or with laser/photoepilation. |
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Authors:
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Ulrike Blume-Peytavi; Susanne Hahn |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Dermatologic therapy Volume: 21 ISSN: 1529-8019 ISO Abbreviation: Dermatol Ther Publication Date: 2008 Sep-Oct |
Date Detail:
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Created Date: 2008-10-10 Completed Date: 2009-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9700070 Medline TA: Dermatol Ther Country: Denmark |
Other Details:
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Languages: eng Pagination: 329-39 Citation Subset: IM |
Affiliation:
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Department of Dermatology and Allergy, Clinical Research Center for Hair and Skin Science, Charité-Universitätsmedizin Berlin, Berlin, Germany. ulrike.blume-peytavi@charite.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Androgen Antagonists
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therapeutic use* Contraceptives, Oral, Hormonal / therapeutic use* Enzyme Inhibitors / therapeutic use* Female Hirsutism / drug therapy* Humans Hypoglycemic Agents / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Androgen Antagonists; 0/Contraceptives, Oral, Hormonal; 0/Enzyme Inhibitors; 0/Hypoglycemic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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