Document Detail

Medical treatment of endometriosis: a comparative trial.
MedLine Citation:
PMID:  395519     Owner:  NLM     Status:  MEDLINE    
In a comparison of danazol, and mestranol with norethynodrel (Enavid, Searle) in the treatment of endometriosis danazol was shown to be superior. Danazol is however relatively ineffective when large tumours or extensive adhesions are present and such patients will usually need a surgical operation. Women who have completed their families and who have severe symptoms will be better treated by hysterectomy. Treatment with danazol is indicated for young women with mild or moderate endometriosis. Danazol treatment may also be given postoperatively after conservative operations.
A D Noble; A T Letchworth
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  55 Suppl 5     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  1979  
Date Detail:
Created Date:  1980-05-23     Completed Date:  1980-05-23     Revised Date:  2009-10-22    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  37-9     Citation Subset:  IM    
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MeSH Terms
Body Weight / drug effects
Clinical Trials as Topic
Danazol / adverse effects,  therapeutic use*
Drug Combinations
Endometriosis / drug therapy*
Genital Neoplasms, Female / drug therapy*
Mestranol / therapeutic use
Norethynodrel / therapeutic use
Pregnadienes / therapeutic use*
Reg. No./Substance:
0/Drug Combinations; 0/Pregnadienes; 17230-88-5/Danazol; 68-23-5/Norethynodrel; 72-33-3/Mestranol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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