| Medical termination of pregnancy in acute intermittent porphyria. | |
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MedLine Citation:
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PMID: 16514240 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute intermittent porphyria is a rare autosomal dominant disease characterized by acute attacks of neuropsychiatric and neurovisceral dysfunction. In pregnancy, exacerbation of attacks in the form of seizures and acute abdomen occur due to hormonal changes. We report the case of a young woman presenting at 8 weeks of gestation requesting pregnancy termination. The patient suffered several episodes of acute abdomen and seizures in a prior pregnancy before the diagnosis was clinched. This case is reported because of its rarity and the limited obstetric experience of this disorder. Proper management depends on avoidance of precipitating factors. Anaesthetic drug safety in porphyria is reviewed and the choice of regional anaesthesia discussed. |
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Authors:
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Meenakshi T Sahu; Shalini Rajaram; Ashok Kumar Saxena; Neerja Goel; Surveen Ghumman |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2006-03-02 |
Journal Detail:
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Title: Gynecologic and obstetric investigation Volume: 62 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 2006 |
Date Detail:
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Created Date: 2006-07-03 Completed Date: 2006-12-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: Switzerland |
Other Details:
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Languages: eng Pagination: 38-40 Citation Subset: IM |
Copyright Information:
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2006 S. Karger AG, Basel |
Affiliation:
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Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents, Nonsteroidal
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administration & dosage* Abortion, Induced* Adult Cesarean Section Female Humans Misoprostol / administration & dosage* Porphyria, Acute Intermittent / complications, diagnosis, physiopathology* Pregnancy Pregnancy Complications / physiopathology* Pregnancy Trimester, First |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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