| Medical surveillance studies of workers exposed to low level benzene. | |
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MedLine Citation:
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PMID: 8670009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The paper presents th results of an investigation of haematotoxicity in workers exposed to low benzene concentrations. Forty-seven female workers in the shoemaking industry, exposed to solvent mixture and twenty-seven non-exposed controls were examined. Benzene concentrations in the working atmosphere ranged from 1.9 to 14.8 ppm. Significant differences in the levels of benzene in blood and phenols in pre- and post-shift urine between the exposed and control groups confirmed benzene exposure. Haemoglobin level and mean corpuscular haemoglobin concentration were significantly lower, and mean corpuscular volume was higher in the shoemaking workers than in controls. In the subgroup of shoemaking workers exposed to benzene concentrations of 5 ppm or lower, no differences in haematological parameters were found. In conclusion, exposure to a benzene concentration lower than 5 ppm does not appear to produce an increased level of abnormal haematological outcomes detectable in routine medical surveillance. The results of the study corroborate the present maximum permissible concentrations (5 ppm) as a protective limit preventing the onset of haematotoxic non-leukemogenic effects of chronic benzene exposure. |
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Authors:
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A Bogadi-Sare; R Turk; M Zavalić |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Arhiv za higijenu rada i toksikologiju Volume: 46 ISSN: 0004-1254 ISO Abbreviation: Arh Hig Rada Toksikol Publication Date: 1995 Dec |
Date Detail:
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Created Date: 1996-08-07 Completed Date: 1996-08-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0373100 Medline TA: Arh Hig Rada Toksikol Country: CROATIA |
Other Details:
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Languages: eng Pagination: 391-8 Citation Subset: IM |
Affiliation:
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Institute for Medical Research and Occupational Health, Zagreb, Croatia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Air Pollutants, Occupational / adverse effects Benzene / adverse effects* Erythrocyte Indices / drug effects* Female Hemoglobins / analysis, drug effects* Humans Middle Aged Occupational Exposure* Solvents / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Air Pollutants, Occupational; 0/Hemoglobins; 0/Solvents; 71-43-2/Benzene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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