| Medical, nutritional and technological properties of lactulose. An update. | |
| | |
MedLine Citation:
|
PMID: 12420112 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The undigestable disaccharide lactulose has been in medical use for over 40 years, mainly in the treatment of portosystemic encephalopathy and of constipation. Pharmacodynamics of lactulose make it an efficacious and safe drug in these indications. But the reason for its numerous potential benefits are under research now. The major principle of action is the promotion of growth and activity of lactic acid bacteria in the gut which counteract detrimental species such as clostridia or salmonellae. This shows that prebiotic action, if used accordingly, can have medically significant effects. The mechanism of action, medical and prebiotic effects, veterinary uses, and technological properties of lactulose, e. g. in yoghurt production are reviewed. |
| | |
Authors:
|
Christian Schumann |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: European journal of nutrition Volume: 41 Suppl 1 ISSN: 1436-6207 ISO Abbreviation: Eur J Nutr Publication Date: 2002 Nov |
Date Detail:
|
Created Date: 2002-11-06 Completed Date: 2003-05-20 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 100888704 Medline TA: Eur J Nutr Country: Germany |
Other Details:
|
Languages: eng Pagination: I17-25 Citation Subset: IM |
Affiliation:
|
Solvay Pharmaceuticals GmbH, Postfach 220, 30002 Hannover, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bile Acids and Salts / metabolism Carrier State / drug therapy Constipation / drug therapy, prevention & control Endotoxins / antagonists & inhibitors Gastrointestinal Agents / therapeutic use Gastrointestinal Diseases / drug therapy*, prevention & control Hepatic Encephalopathy / drug therapy, prevention & control Humans Intestinal Absorption / drug effects Lactobacillus / growth & development* Lactulose / chemistry, diagnostic use, physiology*, therapeutic use Neoplasms / prevention & control Salmonella Infections / drug therapy |
| Chemical | |
Reg. No./Substance:
|
0/Bile Acids and Salts; 0/Endotoxins; 0/Gastrointestinal Agents; 4618-18-2/Lactulose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Relationship of prebiotics and food to intestinal microflora.
Next Document: Effects of lactulose on the intestinal microflora of periparturient sows and their piglets.