| Medical management of ischemic stuttering priapism: a contemporary review of the literature. | |
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MedLine Citation:
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PMID: 22057380 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Priapism is defined as a prolonged and persistent erection of the penis without sexual stimulation. This is a poorly understood disease process with little information on the pathophysiology of this erectile disorder. Complications from this disorder are devastating due to the irreversible erectile damage and resultant erectile dysfunction (ED). Stuttering priapism, though relatively rare, affects a high prevalence of men with sickle-cell disease (SCD) and presents a challenging problem with guidelines for treatment lacking or resulting in permanent ED. The mechanisms involved in the development of priapism in this cohort are poorly characterized; therefore, medical management of priapism represents a therapeutic challenge to urologists. Additional research is warranted, so we can effectively target treatments for these patients with prevention as the goal. This review gives an introduction to stuttering priapism and its clinical significance, specifically with regards to the patient with SCD. Additionally, the proposed mechanisms behind its pathophysiology and a summary of the current and future targets for medical management are discussed.Asian Journal of Andrology advance online publication, 7 November 2011; doi:10.1038/aja.2011.114. |
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Authors:
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Helen R Levey; Omer Kutlu; Trinity J Bivalacqua |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-07 |
Journal Detail:
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Title: Asian journal of andrology Volume: - ISSN: 1745-7262 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100942132 Medline TA: Asian J Androl Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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The Arthur Smith Institute for Urology, North Shore - Long Island Jewish Health System, New Hyde Park, NY 11010, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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