| Medical management of interstitial pregnancy with a retained IUD. A case report. | |
| | |
MedLine Citation:
|
PMID: 10900583 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Systemic methotrexate therapy for interstitial pregnancy has an increased failure rate as compared to other ectopic locations. No case of interstitial pregnancy with a retained intrauterine device (IUD) has been reported on before. CASE: An asymptomatic, 21-year-old woman presented with a positive pregnancy test and a retained IUD. Vaginal ultrasound revealed a left interstitial pregnancy. Diagnostic laparoscopy was followed by a single dose of methotrexate (50 mg/m2). Five days later, a marked increase in the human chorionic gonadotropin level was followed by a second course (four doses) of methotrexate, 1 mg/kg, alternating with 0.1 mg/kg of leucovorin. Concomitant Chlamydia was treated with azithromycin, and the IUD was expelled spontaneously. CONCLUSION: Medical management of interstitial pregnancy may prevent surgery that limits future fertility, but the evidence suggests that more than one dose of methotrexate may be required. |
| | |
Authors:
|
J W McBroom |
Related Documents
:
|
7691303 - Methotrexate treatment for cervical pregnancy: experience of four cases. 11172133 - Three conservative approaches to treatment of interstitial pregnancy. 1555703 - Sperm creatine phosphokinase m-isoform ratios and fertilizing potential of men: a blind... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: The Journal of reproductive medicine Volume: 45 ISSN: 0024-7758 ISO Abbreviation: J Reprod Med Publication Date: 2000 Jun |
Date Detail:
|
Created Date: 2000-10-25 Completed Date: 2000-12-07 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0173343 Medline TA: J Reprod Med Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 490-2 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA. j_mcbroom@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abortifacient Agents, Nonsteroidal
/
therapeutic use* Abortion, Induced Adult Anti-Bacterial Agents / therapeutic use Azithromycin / therapeutic use Chlamydia Infections / complications, drug therapy Diagnosis, Differential Drug Therapy, Combination Female Humans Intrauterine Devices* Leucovorin / therapeutic use Methotrexate / therapeutic use* Pregnancy Pregnancy, Ectopic / complications, diagnosis, drug therapy* Vaginal Diseases / complications, drug therapy |
| Chemical | |
Reg. No./Substance:
|
0/Abortifacient Agents, Nonsteroidal; 0/Anti-Bacterial Agents; 58-05-9/Leucovorin; 59-05-2/Methotrexate; 83905-01-5/Azithromycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clinical use of nafarelin in the treatment of leiomyomas. A review of the literature.
Next Document: Vulvitis attributed to hypersensitivity to estrogen. A report of 11 cases.