Document Detail

Medical management of eosinophilic granuloma of the cervical spine.
MedLine Citation:
PMID:  10708359     Owner:  NLM     Status:  MEDLINE    
We report a case of eosinophilic granuloma involving the vertebral bodies of the cervical spine in a 33-month-old girl. This lesion was diagnosed by needle biopsy and treated with prednisone and vinblastine therapy along with immobilization in a Minerva brace. The child has done well over a 9-month follow-up and has shown MRI evidence of resolution of the lesion, reestablishment of structural integrity within the cervical spine and potential reconstitution of the involved vertebral bodies.
E I Levy; A Scarrow; R C Hamilton; M R Wollman; C Fitz; I F Pollack
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurosurgery     Volume:  31     ISSN:  1016-2291     ISO Abbreviation:  Pediatr Neurosurg     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2000-03-31     Completed Date:  2000-03-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9114967     Medline TA:  Pediatr Neurosurg     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  159-62     Citation Subset:  IM    
Department of Neurosurgery, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, PA 15213, USA.
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MeSH Terms
Anti-Inflammatory Agents / administration & dosage*
Antineoplastic Agents, Phytogenic / administration & dosage*
Biopsy, Needle
Cervical Vertebrae* / pathology
Child, Preschool
Drug Therapy, Combination
Eosinophilic Granuloma / drug therapy*,  pathology
Follow-Up Studies
Magnetic Resonance Imaging
Prednisone / administration & dosage*
Spinal Diseases / drug therapy*,  pathology
Vinblastine / administration & dosage*
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Antineoplastic Agents, Phytogenic; 53-03-2/Prednisone; 865-21-4/Vinblastine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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