Document Detail

Medical management of ectopic pregnancy.
MedLine Citation:
PMID:  22510624     Owner:  NLM     Status:  In-Data-Review    
The use of medical management of ectopic pregnancy has become an accepted alternative to surgical therapy. Methotrexate, a folic acid antagonist, is the most widely studied agent. The most commonly used protocol consists of methotrexate 50 mg/m of actual body weight. Assessment of human chorionic gonadotropin (hCG) levels is repeated on days 4 and 7. Repeat methotrexate dosing is performed for hCG drops <15%. Contraindications include hemodynamically unstable patients or those with elevated liver enzymes, low white blood count, or abnormal renal function. hCG levels are most predictive of success. A success rate of above 90% is achievable.
Gary H Lipscomb
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  55     ISSN:  1532-5520     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-04-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  424-32     Citation Subset:  IM    
Departments of Family Medicine; Obstetrics and Gynecology, University of Tennessee Health Science Center, Memphis, Tennessee.
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