| Medical management of early pregnancy failure: efficacy. | |
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MedLine Citation:
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PMID: 18825609 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Early pregnancy failure is a common pregnancy complication. This article reviews the efficacy of medical management of early pregnancy failure. Nonsurgical treatments, including expectant and medical management, are reasonable alternatives to surgical management depending on the clinical situation and the patient's requests. Possible regimens in medical management of early pregnancy failure include misoprostol alone or mifepristone in conjunction with misoprostol. However, many studies of medical management may underestimate success rates due to inconsistent inclusion criteria, different dosing regimens, and varying definitions of failed treatment. Clinicians need to understand the range of efficacy of these regimens to provide appropriate counseling to patients. |
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Authors:
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Beatrice A Chen; Mitchell D Creinin |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article; Review Date: 2008-09-29 |
Journal Detail:
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Title: Seminars in reproductive medicine Volume: 26 ISSN: 1526-4564 ISO Abbreviation: Semin. Reprod. Med. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-09-30 Completed Date: 2009-01-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100909394 Medline TA: Semin Reprod Med Country: United States |
Other Details:
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Languages: eng Pagination: 411-22 Citation Subset: IM |
Affiliation:
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Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA. chenba@upmc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents
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administration & dosage,
adverse effects,
therapeutic use* Abortion, Spontaneous / drug therapy*, surgery Female Humans Mifepristone / administration & dosage, adverse effects, therapeutic use Misoprostol / administration & dosage, adverse effects, therapeutic use Pregnancy Pregnancy Trimester, First* Randomized Controlled Trials as Topic Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents; 59122-46-2/Misoprostol; 84371-65-3/Mifepristone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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