Document Detail

Medical dissolution of feline struvite urocystoliths.
MedLine Citation:
PMID:  2329073     Owner:  NLM     Status:  MEDLINE    
The efficacy of a diet designed to facilitate dissolution of feline magnesium ammonium phosphate (struvite) uroliths was evaluated in 30 cases of urolithiasis, sterile struvite uroliths dissolved in a mean of 36 days after initiation of dietary treatment. In 5 cases of urolithiasis, struvite urocystoliths associated with urease-negative bacterial urinary tract infection dissolved in a mean of 23 days after initiation of dietary and antimicrobial treatment. In 3 cases of urolithiasis, struvite urocystoliths associated with urease-positive staphylococcal urinary tract infection dissolved in a mean of 79 days after initiation of dietary and antimicrobial treatment. Dissolution of uroliths in cats fed the treatment diet was associated with concomitant remission of dysuria, hematuria, and pyuria, and reduction in urine pH and struvite crystalluria. In one case, a urocystolith composed of 100% ammonium urate, and in another case, a urolith composed of 60% calcium phosphate, 20% calcium oxalate, and 20% magnesium ammonium phosphate did not dissolve.
C A Osborne; J P Lulich; J M Kruger; D J Polzin; G R Johnston; R A Kroll
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  196     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-05-31     Completed Date:  1990-05-31     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1053-63     Citation Subset:  IM    
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul 55108.
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MeSH Terms
Amoxicillin / therapeutic use*
Amoxicillin-Potassium Clavulanate Combination
Cat Diseases / diet therapy*,  radiography
Clavulanic Acids / therapeutic use*
Drug Therapy, Combination / therapeutic use
Follow-Up Studies
Hydrogen-Ion Concentration
Magnesium / analysis,  urine
Magnesium Compounds*
Phosphates / analysis,  urine
Specific Gravity
Time Factors
Urinary Calculi / analysis,  diet therapy,  radiography,  urine,  veterinary*
Urinary Tract Infections / complications,  drug therapy,  veterinary
Reg. No./Substance:
0/Clavulanic Acids; 0/Magnesium Compounds; 0/Phosphates; 15490-91-2/struvite; 26787-78-0/Amoxicillin; 7439-95-4/Magnesium; 74469-00-4/Amoxicillin-Potassium Clavulanate Combination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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