Document Detail


Medical applications of nanoparticles and nanomaterials.
MedLine Citation:
PMID:  19745487     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Current clinical diagnostics and therapeutics platforms are often limited by borderline sensitivity or efficacy levels. These limitations result from low or minimal specificity for the intended target cell or organ, span a multitude of physiological disorders and result in nominal success rates for diagnosis or treatment in many cases. Diagnosis and treatment of diseases such as cancer or viral infections require next generation medical methods. Nanotechnology has the potential to significantly address diagnostics and therapeutics sensitivity and resulting unwanted side effects by providing extremely precise reagents and tools that allow for unparalleled detection and treatment at the clinical level. This is accomplished through extremely controlled nanofabrication methodologies which result in the generation of molecularly defined nanoscale materials and devices that harbor known physical properties unique to each material in question and useful for particular medical applications. The further precise targeting of these materials to specific sites within the body allows for an added layer of accuracy and potency. Research in this area is quickly advancing to the point of providing a comprehensive portfolio of nanotechnology-based diagnostic and therapeutic platforms that will be unparalleled in sensitivity, specificity and elimination of unwanted side effects.
Authors:
Rob Burgess
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Studies in health technology and informatics     Volume:  149     ISSN:  0926-9630     ISO Abbreviation:  Stud Health Technol Inform     Publication Date:  2009  
Date Detail:
Created Date:  2009-09-11     Completed Date:  2010-01-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214582     Medline TA:  Stud Health Technol Inform     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  257-83     Citation Subset:  T    
Affiliation:
Medical Nanotechnologies, Inc.
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MeSH Terms
Descriptor/Qualifier:
Diagnostic Techniques and Procedures
Humans
Nanoparticles*
Neoplasms / diagnosis,  drug therapy
Primary Health Care*
Stem Cells
Tissue Engineering

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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