| Medical Management of Peripheral Arterial Disease: Bridging the "Gap"? | |
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MedLine Citation:
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PMID: 22874582 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Peripheral artery disease (PAD) is estimated to affect 27 million individuals in Europe and North America and its prevalence is increasing in concert with recent demographic and risk factor trends.(1) The majority of patients with PAD are either asymptomatic or have atypical leg symptoms, with classical claudication in only 10-35%, therefore detection is elusive unless actively sought.(2) Given shared risk factors, it is axiomatic that there exists a high co-prevalence of atherosclerosis in other vascular beds including the coronary arteries in PAD patients. However, PAD disproportionately affects the elderly, non-whites, and women compared with CAD alone.(3, 4) The actual co-prevalence of CAD in patients with established PAD depends on how closely it is searched for, with clinical history and ECG detecting only 20-40% of co-existing disease whereas cardiac catheterization detects CAD in as many as 90% of PAD patients.(5, 6). |
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Authors:
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Christopher D Owens; Michael S Conte |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-8 |
Journal Detail:
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Title: Circulation Volume: - ISSN: 1524-4539 ISO Abbreviation: Circulation Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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University of California, San Francisco, San Francisco, CA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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