| Mediation of calcium adaptation by 1,25-dihydroxycholecalciferol. | |
| | |
MedLine Citation:
|
PMID: 908954 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vitamin D-depleted chicks which were repleted with 25-hydroxycholecalciferol adapted to the feeding of a low or high calcium diet by respectively increasing or decreasing their rate of intestinal calcium absorption. The synthesis of 1,25-dihydroxycholecalciferol in chicks fed differing calcium diets correlated directly with intestinal calcium absorption activity, suggesting that the intestinal calcium adaptation response is mediated by the modulation of kidney 25-hydroxycholecalciferol-1-hydroxylase activity. This view was strongly supported by the demonstration that repletion of the chicks with 1,25-dihydroxycholecalciferol eliminated the ability of the chicks to adjust their rates of intestinal calcium absorption to dietary levels of calcium. |
| | |
Authors:
|
J L Omdahl; H F DeLuca |
Related Documents
:
|
11943604 - The protective effect of calcium against genotoxicity of lead acetate administration on... 978574 - The secretion of citrate into milk. 20416434 - In vitro sustained release of calcium ions and ph maintenance from different vehicles c... 15889734 - Effect of a plant growth regulator prohexadione-calcium on insect pests of apple and pear. 7585834 - Ca(2+)-growth coupling in angiotensin ii-induced hypertrophy in cultured rat cardiac ce... 6797354 - Induction of acrosomal reaction in sperm with ionophore a23187 and calcium. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: The Journal of nutrition Volume: 107 ISSN: 0022-3166 ISO Abbreviation: J. Nutr. Publication Date: 1977 Nov |
Date Detail:
|
Created Date: 1977-11-30 Completed Date: 1977-11-30 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0404243 Medline TA: J Nutr Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1975-80 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
25-Hydroxyvitamin D3 1-alpha-Hydroxylase
/
metabolism Adaptation, Physiological Animals Calcium, Dietary / metabolism* Dihydroxycholecalciferols / pharmacology* Hydroxycholecalciferols / metabolism, pharmacology* Intestinal Absorption / drug effects Kidney / enzymology Male |
| Chemical | |
Reg. No./Substance:
|
0/Calcium, Dietary; 0/Dihydroxycholecalciferols; 0/Hydroxycholecalciferols; EC 1.14.-/25-Hydroxyvitamin D3 1-alpha-Hydroxylase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A multifactor analysis of growth in the rat epididymal fat pad.
Next Document: Effect of treadmill speeds and slopes on voluntary exercise in rats.