Document Detail

Mediastinitis presenting as pyrexia of unknown origin.
MedLine Citation:
PMID:  12723660     Owner:  NLM     Status:  MEDLINE    
A 55 year old female was admitted as a case of pyrexia of unknown origin (PUO) of 2 months duration. She had developed throat ache, progressive dysphagia for both solids and liquids, dry cough and retrosternal pain for one week. Examination revealed fever, tachycardia, tachypnoea and a soft tissue warm tender, erythematous, non-fluctuant swelling in lower anterior neck with chest findings suggestive of bilateral pleural effusion. Plain X-rays of the neck and chest strengthened the clinical suspicion of cellulitis of lower neck with bilateral pleural effusion. CT scan confirmed the radiologic findings and also revealed pericardial effusion and thickening; small mediastinal lymphadenopathy and mediastinitis. Patient responded to parenteral antibiotics (ceftriaxone and metronidazole) and hydrocortisone with complete resolution in 10 days.
A Prakash; N P Singh; A Makhija; D Garg; S Kubba; S K Agarwal
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  51     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-05-01     Completed Date:  2003-05-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  405-7     Citation Subset:  IM    
Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi-110 002.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Anti-Infective Agents / therapeutic use
Ceftriaxone / therapeutic use
Fever of Unknown Origin / etiology*,  radiography
Mediastinitis / complications*,  drug therapy,  radiography
Metronidazole / therapeutic use
Middle Aged
Tomography, X-Ray Computed
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Infective Agents; 443-48-1/Metronidazole; 73384-59-5/Ceftriaxone

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