| Mediastinal germ cell tumor in a child with precocious puberty and Klinefelter syndrome. | |
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MedLine Citation:
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PMID: 9725401 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An 8-year-old boy presented with precocious puberty and a mediastinal mass. A computer search showed that this rare presentation is most common with germ cell tumor of the mediastinum in children with Klinefelter syndrome. The tumor was completely resected after preoperative chemotherapy, and the patient is well 2 years after the operation. In patients with Klinefelter syndrome, germ cell tumors are 50 times more common than in patients without Klinefelter syndrome, usually contain nonseminomatous elements, present at an earlier age, and are seldom testicular in location. |
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Authors:
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G G Bebb; F W Grannis; I B Paz; M L Slovak; R Chilcote |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 66 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1998 Aug |
Date Detail:
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Created Date: 1998-09-11 Completed Date: 1998-09-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 547-8 Citation Subset: AIM; IM |
Affiliation:
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Department of General and Oncologic Surgery, City of Hope National Medical Center, Duarte, California 91010, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child Germinoma / complications*, therapy Humans Klinefelter Syndrome / complications* Male Mediastinal Neoplasms / complications*, therapy Puberty, Precocious / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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